Source: Journal of Virology,
Human seasonal H3 clade 3C3a influenza A viruses (IAV) were detected four times in U.S. pigs from commercial swine farms in Michigan, Illinois, and Virginia in 2019. To evaluate the relative risk of this spillover to the pig population, whole genome sequencing and phylogenetic characterization were conducted, and the results revealed that all eight viral gene segments were closely related to 20182019 H3N2 human seasonal IAV. Next, a series of in vitro viral kinetics, receptor binding, and antigenic characterization studies were performed using a representative A/swine/Virginia/A02478738/2018(H3N2) (SW/VA/19) isolate. Viral replication kinetic studies of SW/VA/19 demonstrated less efficient replication curves than all 10 swine H3N2 viruses tested but higher than three human H3N2 strains. Serial passaging experiments of SW/VA/19 in swine cells did not increase virus replication, but changes at HA amino acid positions 9 and 159 occurred. In swine transmission studies, wild-type SW/VA/19 was shed in nasal secretions and transmitted to all indirect contact pigs, whereas the human seasonal strain A/Switzerland/9715293/2013(H3N2) from the same 3C3a clade failed to transmit. SW/VA/19 induced minimal macroscopic and microscopic lung lesions. Collectively, these findings demonstrate that these human seasonal H3N2 3C3a-like viruses did not require reassortment with endemic swine IAV gene segments for virus shedding and transmission in pigs. Limited detections in the U.S. pig population in the subsequent period of time suggest a yet-unknown restriction factor likely limiting the spread of these viruses in the U.S. pig population.
#aH3n2 #abstract #pigs #research #seasonalInfluenza #USA
2018-2019 seasonal A virus into with demonstrated virus in were not sustained in the pig population
Source: Journal of Virology, ABSTRACTHuman seasonal H3 clade 3C3a influenza A viruses (IAV) were detected four times in U.S. pigs from commercial swine farms in Michigan, Illinois, and Virginia in 2019. To evaluate the relative risk of this spillover to the pig population, whole genome sequencing and
Islands of the Feral Pigs
! in JUKEBOX Ruvide on Spotify: "Detroit" by Pigs Pigs Pigs Pigs Pigs Pigs Pigs
Pigs Pigs Pigs Pigs Pigs Pigs here
Veja a letra da msica Pigs de Pink Floyd
We're up a tiny bit later today. I have put the car outside so the plasterer can park on the drive.
I have got Mum's laundry on the machine, and later this morning we will go out into Manchester to meet up with for lunch.
Since our farm sitting holiday in September, I feel like I have aged 20 years. The gout, the subsequent infection, the ongoing difficulty walking, and all the stress of the building works and faff with the scaffolders is taking it toll on me.
When it is all done I need to scrape off those 20 years and put it back in a cupboard until 2054. Then I can get it out and feel 10 years younger for a while.
The carpenter is back for the wetroom.
He has brought the shower tray and a load of sand and cement.
It looks like there will be a floor being poured today.
Still no sign of the scaffolders.
Pigs Have a Weird Stealth Gene That Transforms Them Into Feral Hogs
This is how a barnyard escapee can quickly resemble a feral hog, growing bigger and hairier in a matter of months.
Got up at 6am this morning (same time as Sue).
We both really needed the early sleep last night, and might need it again tonight.
I have moved our car and parked it at work so it is not in the way of all the builders vans.
Carpenters, and floor screed/shower tray installers should be here today.
I am hoping the scaffolders come back and do a full day's work, without moving my stuff about. for no reason.
A look at the "Pig picture" from the Mountain Fire
Letra da msica Pigs de Pink Floyd
Source: Department of Agriculture,
WASHINGTON, Nov. 6, 2024 - Today, the U.S. Department of Agricultures (USDA) Animal and Plant Health Inspection Service (APHIS) is sharing key updates regarding the detection of HPAI H5N1 in a backyard farm operation in Crook County, Ore., as well as additional information about the agencys proactive efforts to protect livestock, farms and communities from avian influenza.
On Wed., Oct. 30, USDA APHIS announced that H5N1 avian influenza was detected in one of the pigs at this backyard farm, that two pigs tested negative, and tests were pending for two additional pigs. The USDA National Veterinary Services Laboratories (NVSL) has completed testing on the two remaining pigs and has confirmed that one tested positive and met the clinical case definition for HPAI H5N1. Sequencing from this positive sample, while incomplete due to the low level of the virus, indicates infection from the D1.2 genotype of H5N1.
Because the amount of virus from the infected pigs was very low, only partial genomic sequences could be extracted from one of the two samples and these sequences indicate infection with the D1.2 genotype of H5N1. APHIS and the Oregon Department of Agriculture had previously also shared that H5N1 had been detected in poultry on the same farm the samples from the poultry were also found to have the D1.2 genotype.
Genomic sequencing of samples from migratory birds in the area showed very similar sequences, which increases the probability that the pigs and poultry on this farm became infected after coming into contact with infected migratory birds, not dairy cattle or other livestock.
This farm is a non-commercial operation, and the animals were not intended for the commercial food supply. There is no concern about the safety of the nations pork supply as a result of this finding.
Additionally, over the past week APHIS has approved field safety trials for two additional vaccine candidates for H5N1 in cattle, bringing the total number of candidates approved for field trials to four. USDA continues to support the rapid development and timely approval of an H5N1 vaccine for dairy cows, in addition to other species.
Last week, as part of USDAs broader efforts to combat the spread of H5N1, APHIS announced plans to partner with State and animal health officials to enhance testing and monitoring for H5N1, building on measures taken by USDA since the beginning of the avian influenza outbreak. This strategy builds on measure taken by states, as well as national risk mitigation measures including the Federal Order requiring testing of lactating cattle prior to interstate movement, which was announced in April 2024. The state of Colorados bulk milk testing program has been highly successful, with no herds currently containing cattle infected with H5N1 and has helped inform the design of this new milk testing strategy.
In partnership with state veterinarians, USDA will implement a tiered strategy to collect milk samples to better assess where H5N1 is present, with the goal to better inform biosecurity and containment measures, as well as to inform state-led efforts to reduce risk to farm workers who may be in contact with animals infected with H5N1. USDA intends to begin implementation of this strategy within 30 days of the announcement. USDA will continue to work with state and private veterinarians on the final details of implementation, and will share guidance documents soon.
USDA continues to emphasize to farmers nationwide that biosecurity is the best weapon against the spread of H5N1, and farms should practice good biosecurity even if the virus has not been detected in their state or vicinity. Data collected over the past seven months has shown that H5N1 can be transmitted on equipment, people, or other items that move from farm to farm, including between dairies and poultry facilities. USDAs Federal Order to require testing before cattle movement between states has helped limit the spread of H5N1, but local and state efforts to enhance biosecurity measures remain just as important. USDA strongly encourages herd owners to participate in available producer support programs, which help to cover the cost such as biosecurity programming, PPE for employees, and veterinary care. Producers can find more information at aphis.usda.gov, or at your nearest USDA Farm Service Agency county office.
As USDA takes additional steps to protect the health of livestock, the Department will continue to work closely with its federal partners at CDC to protect the health of people and FDA to protect the safety of the food supply. These collective, collaborative efforts have helped protect farmworkers and farmers, the health and welfare of livestock animals, and reaffirmed the safety of the nations food supply. The U.S. government remains committed to addressing this situation with urgency.
Learn more about USDAs response to HPAI in dairy cattle on the APHIS website.
#aH5n1 #avianInfluenza #AVIANINFLUENZA #birdFlu #h5n1 #health #news #oregon #pigs #updates #USA #USDA
Kunekune!
*grunting*
Domestic Milk Intake up 6 million litres in September 2024 when compared with September 2023
Preliminary estimates show a fall of 9.8% in the Agricultural Price Input Index for 2024 when compared with 2023 prices
Source: US Centers for Disease Control and Prevention,
Excerpts
()
November 4, 2024 CDC continues to respond to the public health challenge posed by a multistate outbreak of avian influenza A(H5N1) virus, or H5N1 bird flu, in dairy cows, poultry and other animals in the United States. CDC is working in collaboration with the U.S. Department of Agriculture (USDA), the Food and Drug Administration (FDA), Administration for Strategic Preparedness and Response (ASPR), state public health and animal health officials, and other partners using a One Health approach.
Since April 2024, CDC, working with state public health departments, has confirmed H5 bird flu infections in 44 people in the United States. Nineteen of these cases were associated with exposure to H5N1 bird flu-infected poultry and 24 were associated with exposure to sick or infected dairy cows AB. The source of the exposure in one case, which was reported by Missouri on September 6, could not be determined. Serological testing of the contacts of the Missouri case have been reported, and that investigation has concluded.
The 44 cases include 20 cases in dairy farm workers in California, three of which were confirmed by CDC last week and three on Monday, November 4 nine cases in poultry farm workers in Washington state, three of which were confirmed by CDC last week and one case associated with the Washington poultry outbreak that was confirmed by CDC last week and is pending jurisdiction assignment. Not included in that count are four probable cases one in a California dairy farm worker and three in Washington state poultry farm workers. While these probable cases were negative on confirmatory testing at CDC, all four met the Council of State and Territorial Epidemiologists (CSTE) probable case definition and have been reported by the states.
Cases in California and Washington have occurred in workers on affected farms. All available data so far suggest sporadic instances of animal-to-human spread. The farm workers in California and Washington state all described mild symptoms, many with eye redness or discharge (conjunctivitis). Some workers who tested positive in Washington reported some mild upper respiratory symptoms. None of the workers were hospitalized. Updated case counts, including by state and source of exposure, are reflected in a table on CDCs website. To date, person-to-person spread of H5 bird flu has not been identified in the United States. CDC believes the immediate risk to the general public from H5 bird flu remains low, but people with exposure to infected animals are at higher risk of infection.
On the animal health side, since March 2024, USDA has confirmed infected cattle in 440 dairy herds in 15 U.S. states. The number of affected herds continues to grow nationally, with almost all new infections identified in herds in California. USDA reports that, since April 2024, there have been H5 detections in 45 commercial poultry flocks and 30 backyard flocks, for a total of 22.37 million birds affected.
Among other activities reported in previous spotlights and ongoing, recent highlights of CDCs response to this include:
CDC posted a spotlight describing the results of CDCs first study investigating the effects in ferrets of an avian influenza A(H5N1) virus isolated from a human case in the United States. The study, published on October 28 in the journal Nature, found that when 12 laboratory ferrets were infected with a virus isolated from a human case in Texas (A/Texas/37/2024), all 12 experienced severe and fatal disease. The study also found that this virus efficiently transmitted from infected ferrets to healthy ferrets in the presence of direct contact and, less efficiently, via fomites and respiratory droplets. Preliminary findings from this study, first shared in June 2024, were instrumental in informing early risk assessments related to this outbreak.
To date, CDC has confirmed nine human cases of H5 bird flu in poultry farm workers in Washington state. Genetic sequencing of three of these cases confirms that all are avian influenza A(H5N1) viruses from clade 2.3.4.4b and that all are closely related genetically to the viruses causing infections in poultry on the farm where depopulation was conducted. CDC has successfully obtained partial gene sequences for viruses from three cases in Washington (A/Washington/239/2024, A/Washington/240/2024, A/Washington/247/2024) with other cases pending sequence analysis.
That sequencing information showed that the viruses hemagglutinin (HA) is closely related to candidate vaccine viruses (CVV) and that there were no changes in the HA associated with increased infectivity or transmissibility among people. Additionally, there were no mutations associated with reduced susceptibility to available neuraminidase inhibitor treatments and no mutations identified in other genes indicating additional mammalian adaptation. Genetic data have been posted in GISAID and GenBank. Additional data will be posted as they become available. CDC has successfully isolated virus from specimens from three of the nine cases. Attempts to isolate virus from additional specimens are ongoing. Antigenic characterization and antiviral susceptibility testing are underway. Antigenic characterization will inform whether existing H5 bird flu candidate vaccine viruses (CVVs) would provide good inhibition of these viruses.
On Wednesday, October 30, 2024, USDA reported an avian influenza A(H5N1) virus infection in a pig on a backyard farm in Oregon. This is the first time an H5 bird flu infection has been reported in a pig in the United States. Sequence data from birds in the avian influenza A(H5) virus outbreak on this backyard farm showed no mutations that caused concerns related to disease severity or adaptability to humans. The discovery that an avian influenza A virus has infected a new mammal species is always concerning, especially when the virus is detected in pigs, which are susceptible to influenza viruses circulating in pigs, humans, birds, and other species. These viruses can swap genes through a process called genetic reassortment, which can occur when two (or more) influenza viruses infect a single host. Reassortment can result in the emergence of new influenza A viruses with new or different properties, such as the ability to spread more easily among animals or people. Reassortment events have happened in pigs in the past. A series of reassortment events in pigs is believed to have caused the 2009 influenza A(H1N1) pandemic. Based on available information, the risk to the general public remains low however, CDC is continuing to gather information.
A multilingual CDC field team continues to assist the California Department of Public Health in its efforts to learn more about how the outbreak in California began and how to lower the risk to farm workers with exposure to infected cows. Two staff members are on the ground in California, and additional staff are ready to deploy if needed. CDC staff are assisting with active surveillance efforts, including field assessments of suspected cases and household contacts testing and treatment and dissemination of information to farm workers and the community. A separate CDC field team has returned from deployment to Washington state but continues to work remotely with the local health department on data management and epidemiological summaries. There is no evidence of any person-to-person spread in either of the two states or anywhere in the United States.
As noted above, CDC has so far confirmed nine cases in Washington.
CDC continues to support states that are monitoring people with exposure to cows, birds, or other domestic or wild animals infected, or potentially infected, with H5N1 bird flu. To date, more than 6,700 people have been monitored as a result of their exposure to infected or potentially infected animals, and at least 340 people who have developed flu-like symptoms have been tested as part of this targeted, situation-specific testing. More information on monitoring can be found at Symptom Monitoring Among Persons Exposed to HPAI.
In addition, since February 25, 2024, more than 57,000 specimens have been tested for avian influenza A(H5) virus or other novel influenza viruses at public health labs. One of the specimens, collected as a part of routine surveillance, was identified as presumptive positive for avian influenza A(H5) virus and was confirmed as H5N1 bird flu positive by CDC.
CDC also continues to monitor flu surveillance data using CDCs 2024-2025 influenza surveillance strategy, especially in areas where avian influenza A(H5N1) viruses have been detected in dairy cows or other animals, for any unusual trends, including in flu-like illness, conjunctivitis, or influenza virus activity. Overall, for the most recent week of data, CDC flu surveillance systems show no indicators of unusual flu activity in people.
()
#aH5n1 #avianInfluenza #AVIANINFLUENZA #birdFlu #california #h5n1 #health #human #news #oregon #pigs #poultry #updates #USCDC #USA #washington
Pig steals pumpkins, dog and cat work in grocery store, dog reunites with owner, happy capybara, and more.
On the wild pigs that roam the Hawaiian islands, wrecking havoc on any unprotected gardens: "Hawaiian pigs are the product of 200 years of interbreeding between the pint-sized Polynesian pigs from Asia and the much larger breeds developed by Europeans. They possess a globally distinct mix of genes, including a unique mutation that controls their black coat color." -
One of the easiest ways to connect with people in our area is to ask "so, do you have many problems with pigs" Pigs are truly a force of nature. Sometimes they take chickens. Sometimes they ruin lawns with their rooting. They come quietly in the night when it's raining, with the sound of the rain covering their sounds. They are smart, sneaky, very strong, and very determined. I've had pigs break into plastic tubs in the shed, and eat all the cans of cat food (I found the cans chewed flat). If they find an unprotected source of food (like a garden with a hole in the fence), they'll come back night after night until everything is gone. They are the fruit of the meadow and are an important part of many people's diets. They live here and we live with them. They are PIG!
Matilda and the Brave Escape Narrated by Bella Ramsey Animated Short Film
How Pigs Shaped Medieval Life: Surprising Roles in Politics, Warfare, and Law
How Pigs Shaped Medieval Life: Surprising Roles in Politics, Warfare, and Law
Pigs, in particular, are sometimes called a mixing vessel, for flu viruses because they can pool together human and bird flu viruses at the same time, STAT reported. The fear is that various viruses could coexist in the body, swap genes, and produce a new strain that can more efficiently spread between people.
Earthling Ed lanceert vanavond 8 uur op zijn YouTube kanaal een documentaire over Matilda. Een varken die in 2021 ontsnapte en in een bos haar kinderen baarde. Ze werd wereldnieuws. Het is een verhaal van hoop en inspiratie.
Definitely not a good thing...
Bird Flu Is One Step Closer to Mixing with Seasonal Flu Virus and Becoming a Pandemic
Humans and pigs could both serve as mixing vessels for a bird fluseasonal flu hybrid, posing a risk of wider spread
As the H5N1 avian influenza virus continues its rampage through U.S. dairy cow herds, it has also infected human farm workers. A different strain has also infected workers on poultry farms, most recently in Washington State. On Wednesday the U.S. Department of Agriculture announced that the virus had been detected in a pig for the first time at a farm in Oregon. Now, as the usual seasonal flu season approaches, some health experts wonder if it might give bird flu a dangerous boost.
Over 60,000 acres of agricultural land were sold nationally in 2023 for a median price of 9,084 per acre
Source: Xinhua,
Excerpt
() Some experts point out that pigs are susceptible to multiple types of avian influenza viruses, and then act as incubators, causing avian influenza viruses and swine influenza viruses to recombine, posing a greater threat to humans.
Mary Calhern, a professor of veterinary medicine at the University of Minnesota, said the findings were a warning to pig farmers to be vigilant against further infection. If the avian influenza virus could spread to other herds, people need to develop more response plans. ()
#aH5n1 #avianInfluenza #pandemicInfluenza #pigs #USA
detected in for first time in
Source: Xinhua, Excerpt (...) Some experts point out that pigs are susceptible to multiple types of avian influenza viruses, and then act as "incubators", causing avian influenza viruses and swine influenza viruses to recombine, posing a greater threat to humans. Mary Calhern, a professor of veterinary medicine at the University of Minnesota, said the findings were a "
Source: CIDRAP,
Excerpt
Federal officials today announced the first H5N1 avian flu detection in pigs, which was on a backyard farm in Oregon where an outbreak was recently reported in poultry.
()
#aH5n1 #avianInfluenza #pigs #USA
announces first detection in
Source: CIDRAP, Excerpt Federal officials today announced the first H5N1 avian flu detection in pigs, which was on a backyard farm in Oregon where an outbreak was recently reported in poultry. (...)
Letra da msica Pigs de Pink Floyd
I'm A A In Responds To 's " And " .
, a living in , addresses Salvinis made on last week, where 's compared to dogs and pigs.
dont
(2024) Take Action: Big pork is bludgeoning piglets to death Slamming piglets into a concrete floor sounds too horrific to be true, let alone legal. And yet, piglet thumping happens regularly on factory farms.
Celebrity Pigsindeed
The number of Cattle slaughtered in September 2024 increased by 11.5% when compared with September 2023
Stand Up for Pigs Send a letter to the Scottish Government
Entdecken Sie den Text des Liedes Pigs von Pink Floyd
Drawlloween Day 21: Silence of the Hams.